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1

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

Forman, Mark S, Trojanowski, John Q, Lee, Virginia M-Y

Journal:

Nature Medicine

Year:

2004

Language:

english

File:

PDF, 1.25 MB

english, 2004

2

Antibody labeling of bovine neurofilaments: implications on the structure of neurofilament sidearms

Lizanne Mulligan, Brian J. Balinj, Virginia M-Y. Lee, Wallace Ip

Journal:

Journal of Structural Biology

Year:

1991

Language:

english

File:

PDF, 17.59 MB

english, 1991

3

N EURODEGENERATIVE T AUOPATHIES

Lee, Virginia M-Y, Goedert, Michel, Trojanowski, John Q

Journal:

Annual Review of Neuroscience

Year:

2001

Language:

english

File:

PDF, 502 KB

english, 2001

4

Unexpected abundance of pathological tau in progressive supranuclear palsy white matter

Victoria Zhukareva, Sonali Joyce, Teresa Schuck, Vivianna Van Deerlin, Howard Hurtig, Roger Albin, Sid Gilman, Steven Chin, Bruce Miller, John Q. Trojanowski, Virginia M-Y. Lee

Journal:

Annals of Neurology

Year:

2006

Language:

english

File:

PDF, 1.50 MB

english, 2006

5

The cytoskeleton in neurodegenerative diseases

Nigel J Cairns, Virginia M-Y Lee, John Q Trojanowski

Journal:

The Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 464 KB

english, 2004

6

Frontotemporal dementia and tauopathy

Yasumasa Yoshiyama, Virginia M-Y Lee, John Q. Trojanowski

Journal:

Current Neurology and Neuroscience Reports

Year:

2001

Language:

english

File:

PDF, 369 KB

english, 2001

7

Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury

Valeria Conte, Kunihiro Uryu, Scott Fujimoto, Yuemang Yao, Joshua Rokach, Luca Longhi, John Q. Trojanowski, Virginia M-Y. Lee, Tracy K. McIntosh, Domenico Praticò

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 47 KB

english, 2004

8

Is the Initial Insult in Parkinson's Disease and Dementia with Lewy Bodies a Neuritic Dystrophy?

JOHN E. DUDA, BENOIT I. GIASSON, VIRGINIA M-Y. LEE, JOHN Q. TROJANOWSKI

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 425 KB

2003

9

Parkinson's Disease and Related α-Synucleinopathies Are Brain Amyloidoses

JOHN Q. TROJANOWSKI, VIRGINIA M-Y. LEE

Journal:

Annals of the New York Academy of Sciences

Year:

2003

File:

PDF, 132 KB

2003

10

Pathological tau: a loss of normal function or a gain in toxicity?

Trojanowski, John Q, Lee, Virginia M-Y

Journal:

Nature Neuroscience

Year:

2005

Language:

english

File:

PDF, 248 KB

english, 2005

11

Fatal attractions: abnormal protein aggregation and neuron death in Parkinson's disease and Lewy body dementia

Trojanowski, John Q, Goedert, Michel, Iwatsubo, Takeshi, Lee, Virginia M-Y

Journal:

Cell Death & Differentiation

Year:

1998

Language:

english

File:

PDF, 147 KB

english, 1998

12

Vitamin E reduces amyloidosis and improves cognitive function in Tg2576 mice following repetitive concussive brain injury

Valeria Conte, Kunihiro Uryu, Scott Fujimoto, Yuemang Yao, Joshua Rokach, Luca Longhi, John Q. Trojanowski, Virginia M-Y. Lee, Tracy K. McIntosh, Domenico Praticò

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 149 KB

english, 2004

13

TDP-43: a novel neurodegenerative proteinopathy

Mark S Forman, John Q Trojanowski, Virginia M-Y Lee

Journal:

Current Opinion in Neurobiology

Year:

2007

Language:

english

File:

PDF, 557 KB

english, 2007

14

Disruption of the cytoskeleton in Alzheimer's disease

Virginia M-Y Lee

Journal:

Current Opinion in Neurobiology

Year:

1995

Language:

english

File:

PDF, 481 KB

english, 1995

15

Nosology of Parkinson’s Disease: Looking for the Way Out of a Quackmire

Mark S. Forman, Virginia M-Y. Lee, John Q. Trojanowski

Journal:

Year:

2005

Language:

english

File:

PDF, 119 KB

english, 2005

16

More than just two peas in a pod: common amyloidogenic properties of tau and α-synuclein in neurodegenerative diseases

Virginia M-Y Lee, Benoit I Giasson, John Q Trojanowski

Journal:

Trends in Neurosciences

Year:

2004

Language:

english

File:

PDF, 557 KB

english, 2004

17

Brain Trauma Induces Massive Hippocampal Neuron Death Linked to a Surge in β-Amyloid Levels in Mice Overexpressing Mutant Amyloid Precursor Protein

Douglas H. Smith, Michio Nakamura, Tracy K. McIntosh, Jun Wang, Amarís Rodríguez, Xiao-Han Chen, Ramesh Raghupathi, Kathryn E. Saatman, James Clemens, M. Luise Schmidt, Virginia M-Y Lee, John Q. Troja

Journal:

The American Journal of Pathology

Year:

1998

Language:

english

File:

PDF, 1.00 MB

english, 1998

18

β-Secretase revealed: starting gate for race to novel therapies for Alzheimer’s disease

Daniel M Skovronsky, Virginia M-Y Lee

Journal:

Trends in Pharmacological Sciences

Year:

2000

Language:

english

File:

PDF, 81 KB

english, 2000

19

‘Unfolding’ pathways in neurodegenerative disease

Mark S Forman, Virginia M-Y Lee, John Q Trojanowski

Journal:

Trends in Neurosciences

Year:

2003

Language:

english

File:

PDF, 268 KB

english, 2003

20

Increased isoprostane biosynthesis in alzheimer's disease: Correlation of a specific non invasive index of lipid peroxidation with disease severity

Domenico Pratico, Christopher C. Clark, Virginia M-Y. Lee, John Q. Trojanowski, Garret A. FitzGerald

Journal:

Neurobiology of Aging

Year:

2000

Language:

english

File:

PDF, 179 KB

english, 2000

21

Reversible β-pleated sheet formation of a phosphorylated synthetic τ peptide

Emma Lang, Gyorgyi I. Szendrei, Ilona Elekes, Virginia M-Y. Lee, Laszlo Otvos Jr.

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 416 KB

english, 1992

22

Monoclonal and polyclonal antibodies against neural antigens: Diagnostic applications for studies of central and peripheral nervous system tumors

John Q. Trojanowski, Virginia M-Y Lee

Journal:

Human Pathology

Year:

1983

Language:

english

File:

PDF, 1.15 MB

english, 1983

23

Microtubule-stabilising drugs for therapy of Alzheimer’s disease and other neurodegenerative disorders with axonal transport impairments

Trojanowski, John Q, Smith, Amos B, Huryn, Donna, Lee, Virginia M-Y

Journal:

Expert Opinion on Pharmacotherapy

Year:

2005

Language:

english

File:

PDF, 66 KB

english, 2005

24

Clinical and Biochemical Differences in Patients Having Parkinson Disease With vs Without GBA Mutations

Chahine, Lama M., Qiang, Judy, Ashbridge, Emily, Minger, James, Yearout, Dora, Horn, Stacy, Colcher, Amy, Hurtig, Howard I., Lee, Virginia M-Y., Van Deerlin, Vivianna M., Leverenz, James B., Siderowf,

Journal:

Year:

2013

Language:

english

File:

PDF, 365 KB

english, 2013

25

Transmission of alpha-synuclein in Parkinson’s disease

Virginia M-Y Lee

Journal:

Molecular Neurodegeneration

Year:

2013

Language:

english

File:

PDF, 73 KB

english, 2013

26

Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease models

Kim, Hyung-Jun, Raphael, Alya R, LaDow, Eva S, McGurk, Leeanne, Weber, Ross A, Trojanowski, John Q, Lee, Virginia M-Y, Finkbeiner, Steven, Gitler, Aaron D, Bonini, Nancy M

Journal:

Nature Genetics

Year:

2013

Language:

english

File:

PDF, 1.51 MB

english, 2013

27

Addition of exogenous α-synuclein preformed fibrils to primary neuronal cultures to seed recruitment of endogenous α-synuclein to Lewy body and Lewy neurite–like aggregates

Volpicelli-Daley, Laura A, Luk, Kelvin C, Lee, Virginia M-Y

Journal:

Nature Protocols

Year:

2014

Language:

english

File:

PDF, 925 KB

english, 2014

28

Toxicity and Neuronal Infection of a HSV-1 ICP34.5 Mutant in Nude Mice

Lasner, Todd M, Tal-Singer, Ruth, Kesari, Santosh, Lee, Virginia M-Y, Trojanowski, John Q, Fraser, Nigel W

Journal:

Journal of NeuroVirology

Year:

1998

Language:

english

File:

PDF, 730 KB

english, 1998

29

Aminothienopyridazines as imaging probes of tau pathology: a patent evaluation of WO2013090497

Ballatore, Carlo, Smith, Amos B, Lee, Virginia M-Y, Trojanowski, John Q, Brunden, Kurt R

Journal:

Expert Opinion on Therapeutic Patents

Year:

2014

Language:

english

File:

PDF, 694 KB

english, 2014

30

Differential induction and spread of tau pathology in young PS19 tau transgenic mice following intracerebral injections of pathological tau from Alzheimer’s disease or corticobasal degeneration brains

Boluda, Susana, Iba, Michiyo, Zhang, Bin, Raible, Kevin M., Lee, Virginia M-Y., Trojanowski, John Q.

Journal:

Acta Neuropathologica

Year:

2015

Language:

english

File:

PDF, 13.06 MB

english, 2015

31

Intracellular APP Processing and Aβ Production in Alzheimer Disease

Wilson, Christina A., Doms, Robert W., Lee, Virginia M-Y

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

1999

File:

PDF, 477 KB

1999

32

Accumulation of Intracellular Amyloid-β Peptide (Aβ 1–40) in Mucopolysaccharidosis Brains

Ginsberg, Stephen D., Galvin, James E., Lee, Virginia M-Y, Rorke, Lucy B., Dickson, Dennis W., Wolfe, John H., Jones, Margaret Z., Trojanowski, John Q.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

1999

File:

PDF, 846 KB

1999

33

Myosin Va Binding to Neurofilaments Is Essential for Correct Myosin Va Distribution and Transport and Neurofilament Density

Mala V. Rao, Linda J. Engle, Panaiyur S. Mohan, Aidong Yuan, Dike Qiu, Anne Cataldo, Linda Hassinger, Stephen Jacobsen, Virginia M-Y. Lee, Athena Andreadis, Jean-Pierre Julien, Paul C. Bridgman and Ra

Journal:

The Journal of Cell Biology

Year:

2002

Language:

english

File:

PDF, 3.69 MB

english, 2002

34

Altered microtubule dynamics in neurodegenerative disease: Therapeutic potential of microtubule-stabilizing drugs

Brunden, Kurt R., Lee, Virginia M-Y., Smith, Amos B., Trojanowski, John Q., Ballatore, Carlo

Journal:

Neurobiology of Disease

Year:

2016

Language:

english

File:

PDF, 684 KB

english, 2016

35

PERFORMANCE EVALUATION OF NEW ABSORBANCE-BASED ELISAS FOR MEASURING DIFFERENT ALPHA-SYNUCLEIN (A-SYN) SPECIES IN CSF AND PLASMA

Stoops, Erik, Majbour, Nour, Mauroo, Kimberley, Demeyer, Leentje, Lashuel, Hilal, Trojanowski, John Q., M-Y Lee, Virginia, El Agnaf, Omar, Vanderstichele, Hugo Marcel

Journal:

Alzheimer's & Dementia

Year:

2016

Language:

english

File:

PDF, 578 KB

english, 2016

36

Distinct binding of PET ligands PBB3 and AV-1451 to tau fibril strains in neurodegenerative tauopathies

Ono, Maiko, Sahara, Naruhiko, Kumata, Katsushi, Ji, Bin, Ni, Ruiqing, Koga, Shunsuke, Dickson, Dennis W., Trojanowski, John Q., Lee, Virginia M-Y., Yoshida, Mari, Hozumi, Isao, Yoshiyama, Yasumasa, va

Journal:

Year:

2017

Language:

english

File:

PDF, 2.11 MB

english, 2017

37

CELL-TO-CELL TRANSMISSION OF PATHOLOGICAL TAU: A POTENTIAL MECHANISM OF DISEASE PROGRESSION IN ALZHEIMER'S AND OTHER TAUOPATHIES

M-Y Lee, Virginia

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 260 KB

english, 2017

38

EMERGING CONCEPTS IN BASIC SCIENCE: PANEL SESSION

Holmes, Clive, Grothe, Michel J., Carare, Roxana O., Herrup, Karl, M-Y Lee, Virginia, Williams, Julie

Journal:

Alzheimer's & Dementia

Year:

2017

Language:

english

File:

PDF, 260 KB

english, 2017

39

Apolipoprotein E Highly Correlates with AÎ²PP- and Tau-Related Markers in Human Cerebrospinal Fluid

Vuletic, Simona, Li, Ge, Peskind, Elaine R., Kennedy, Hal, Marcovina, Santica M., Leverenz, James B., Petrie, Eric C., Lee, Virginia M-Y., Galasko, Douglas, Schellenberg, Gerard D., Albers, John J.

Journal:

Journal of Alzheimer's Disease

Year:

2008

File:

PDF, 85 KB

2008

40

Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration

Robinson, John L, Porta, SÃlvia, Garrett, Filip G, Zhang, Panpan, Xie, Sharon X, Suh, EunRan, Van Deerlin, Vivianna M, Abner, Erin L, Jicha, Gregory A, Barber, Justin M, Lee, Virginia M-Y, Lee, Edwar

Journal:

Year:

2020

File:

PDF, 1.36 MB

2020

41

Mechanisms of slow axonal transport of Î±-synuclein

Roy, Subhojit, Winton, Matthew J., Black, Mark M., Trojanowski, John Q., Lee, Virginia M-Y.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2007

File:

PDF, 492 KB

2007